2002 PND Medical Symposium
First Annual Symposium on Pediatric Neurotransmitter Diseases Annals of Neurology #160;Vol 54 Supplement 6 2003
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Darryl C. De Vivo, MD- Chair
"Functional Aspects of GABA Neurotransmitter"
O.C. Snead, MD
"Biogenic Amines-Metabolism and Regulation"
Teodoro Bottliglieri, PhD
"GHB: A Potential Neurotransmitter in Mammalian CNS"
O.C Snead, MD
Session II- Clinical Overview of PNDs
Andrea Gropman-Chair"Aromatic L-Amino Acid Decarboxylase Deficiency"
Kathryn Swoboda , MD
" Tyrosine Hydroxylase Deficiency"
Georg F. Hoffmann, MD
"Segawa Disease (Dominantly Inherited GTP I Cyclohydrolase Deficiency)"
Darryl C. De Vivo, MD
"Succinc Semialdehyde Dehydrogenase (SSADH) Deficiency (4 Hydroxybutyric Aciduria) in Children and Adults"
Phillip Pearl, MD
Session III- Diagnoses and Therapeutic Interventions for PND'
Keith Hyland, PhD- Chair
"The Clinicians's Approach to the Diagnosis of the Patient with a Suspected PND"
Georg F. Hoffmann, MD
"The Lumbar Puncture for Diagnosis of PNDs"
Keith Hyland , PhD
"Therapeutic Interventions for Disorders of Biogenic Amine Metabolism"
Blair Ford, MD
"Vigabatrin and Newer Interventions in SSADH Deficiency"
Andrea Gropman, MD
Summary Discussion -"Strategy Planning for Implementation of Goals and Objectives of the PND Association
Chaired by the Scientific Organization Committee and Invited Speakers
Session IV- Animal Models of PND's
Kathryn Swoboda, MD-Chair
"Animal Models of Catecholamine Defects"
Marc Caron, MD
"New Therapeutic Insights form a Murine Model of SSADH Deficiency"
K. Michael Gibson, PhD
"The hph- mouse , A Model of GTP I Cyclohydrolase Deficiency"
Keith Hyland, PhD
Session V- Future Directions for Research and Treatment of PNDsGeorg Hoffmann, MD- Chair
"The Potential Role of Hepatocyte Repopulation in Treating PNDs"
Markus Grompe MD
"Genetic Modification of Human Neuronal Stem Cells"Implications for Brain Repair"
Clive Svendsen, PhD
Summary Discussion- "What are the Future Objectives of the PND Association and How Do We Coordinate to Achieve Our Goals"
Chaired by the Scientific Organizing Committee and Invited Speakers